The Top 22 Best Weight Loss Pills of 2022 Final Word

It’s a new year – and it could be a new you.

With the help of a good weight loss supplement, this year could be better than ever. A good weight loss supplement helps reveal the “new you,” losing weight while complementing the effects of a diet or exercise program.

For the best weight loss results from a science-backed supplement, check our list above and enjoy the best weight loss pills of 2022.

RELATED:Best Fat Burner Supplements – Review the Top Fat Burning Pills

Affiliate Disclosure: The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.

Disclaimer: Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

Weight Loss Pill Benefits: What Does Science Say?

Plenty of studies prove that weight loss pills work for weight loss. We’ll review some of that evidence below.

Caffeine is one of the most popular and proven ways to lose weight. There’s a reason it’s found in so many weight loss supplements. In this study, researchers gave caffeine to a group of 76 obese adults. Researchers observed significant drops in fat mass, waist circumference, and overall weight in the high caffeine intake group.

Fiber is another popular weight loss pill ingredient. You can find plenty of glucomannan supplements, for example, that absorb water in the gut and help you lose weight. In this 2005 study, researchers gave a glucomannan supplement to a group of 176 people and found it helped them lose weight. Other studies have found that up to 95% of American adults do not get their recommended daily fiber intake. Fiber is not just linked to weight loss: it’s also linked to good heart health and other benefits.

Garcinia cambogia extract has been popular for a decade. The small, pumpkin-like fruit contains an active ingredient called hydroxycitric acid (HCA) linked to weight loss. Studies show that HCA may inhibit fat formation, suppress appetite, and boost metabolism. However, there are few large-scale studies in humans verifying the weight loss benefits of garcinia cambogia extract, and we need more research to verify all of these effects.

Many weight loss pills contain green tea extract, including two proven fat-burning ingredients: caffeine and EGCG. We’ve already talked about caffeine. However, EGCG is an antioxidant-like compound that appears to increase the rate of fat burning in the body. Green tea is also well-tolerated by most healthy adults. The L-theanine in green tea could nullify some of the unpleasant side effects of caffeine, including jitters and anxiety.

Conjugated linoleic acid (CLA) has surged in popularity in recent years. It’s a type of fatty acid that appears to be linked to weight loss. If you believe in the power of the keto diet, then CLA supplements may be your new best friend. Although some studies have linked CLA to powerful weight loss results, other studies have been less conclusive. Nevertheless, many people take 3g to 6g of CLA daily to lose weight.

Some of the best weight loss pills are only available via prescription. Qsymia, for example, is one of the most popular weight loss pills available today. The FDA approved Qsymia for weight loss because of impressive clinical trials. In phase I and phase II clinical trials, researchers found that Qsymia led to an average of 10% body weight loss. Qsymia contains a combination of phentermine and topiramate, helping your body lose weight in multiple ways. Physicians may prescribe Qsymia and other weight loss pills to people with a BMI over 30 or those with a BMI over 27 and a related health condition (like type 2 diabetes or high blood pressure).

You may not need a fancy herbal or plant extract to lose weight. Sometimes, all you need is a common mineral like calcium. Some studies have shown that calcium can increase lipolysis (fat burning) while decreasing fat accumulation and absorption.

Some weight loss pills contain capsaicin, the active ingredient in chili peppers that gives them their spiciness. Studies show that capsaicin and other capsaicinoids increase lipid oxidation (fat burning), energy expenditure, and overall weight loss.

Probiotic supplements could help you lose weight. One of the most popular weight loss pills available today, BioFit, only contains probiotics. Probiotics are beneficial bacteria that reside in your digestive tract, helping you break down foods, absorb nutrients, and maintain good immunity. Because of growing research supporting the weight loss benefits of probiotics, some researchers have suggested it’s time to use probiotics to prevent or treat obesity.

Other popular science-backed weight loss pill ingredients include forskolin, chromium, fucoxanthin, raspberry ketones, Yohimbe, and African mango, all of which have some scientific evidence proving they can help with weight loss.

Overall, studies show that taking a good weight loss pill could accelerate weight loss results. By taking the right weight loss supplement daily, you can enjoy powerful fat burning and appetite suppressing benefits, making it easier to maintain a caloric deficit and lose weight.

Weight Loss Pill Dosages

Weight loss pills contain many different ingredients. No specific dosage makes a weight loss pill good or bad. However, we do know the best dosage for particular weight loss ingredients.

Many weight loss pills contain caffeine, for example. A cup of coffee contains 80mg to 120mg of caffeine. This dosage has been shown to boost metabolism and accelerate fat burning. Weight loss pills can contain 50mg to 300mg of caffeine per serving.

There are no specific dosage recommendations for herbal and plant extracts. We know that garcinia cambogia appears to work when used at dosages of 750mg to 1,500mg. However, because hydroxycitric acid (HCA) concentration varies between formulas, no two supplements may be alike.

Follow the recommended dosage instructions on your weight loss pill to ensure maximum effectiveness.

Weight Loss Pill Side Effects

When following the recommended dosage on your weight loss pill, you’re unlikely to experience side effects.

Per FDA regulations, weight loss pills must contain ingredients and dosages that are Generally Recognized As Safe (GRAS). The FDA has verified that these ingredients and dosages are unlikely to cause adverse side effects when taken as directed.

However, all supplements have the chance to lead to minor side effects, including:

  • Upset stomach and other digestive issues
  • Headache
  • Nausea
  • Fatigue
  • Jitters, anxiety, and nervousness

You can reduce the risk of side effects by checking the ingredients label. For example, if you’re sensitive to caffeine, you should avoid weight loss pills containing caffeine.

If you have a medical condition or are taking medication, talk to your doctor before taking weight loss pills or other supplements.

How Do Weight Loss Pills Work?

Weight loss pills contain dozens of different ingredients that work in different ways. However, most weight loss pills are designed to achieve one of four various benefits:

  • Reduce your appetite, making it easier to make healthy food choices and keep a caloric deficit.
  • Increase fat burning by boosting metabolism, allowing you to create a more significant caloric deficit.
  • Inhibit your body’s ability to absorb fat or carbs from the foods you eat.
  • Signal your body to start burning fat for energy in other ways (say, through herbal extracts or BHB ketones).

As you can see, all weight loss pills are linked to the same foundational benefit: they all help you maintain a caloric deficit. The only way to lose weight is by maintaining a caloric deficit.

If you can consistently burn more calories than you consume, then you’ll lose weight. A good weight loss pill can make it easier to maintain a caloric deficit.

Who Should Take a Weight Loss Pill?

Many people take weight loss pills daily to help them lose weight. Some of the people who could benefit from a weight loss pill include:

  • Anyone who wants to kickstart a new diet or exercise program
  • Someone looking to enhance the effects of their diet and exercise program, losing more weight than they would without taking a supplement
  • Those trying to lose weight without much diet or exercise
  • Anyone on a “cutting” phase who wants to reveal toned muscle beneath the fat
  • Someone who wants a safe and sustainable way to lose weight
  • Anyone targeting stubborn fat around the hips, thighs, or tummy that doesn’t seem to disappear with regular dieting or exercise

Maybe you’ve been trying to lose weight for years. Perhaps it’s finally time to start losing weight in the new year. Whatever your situation may be, a good weight loss pill could help.

How We Ranked The Best Weight Loss Pills

Every weight loss pill claims to help you lose weight. Unfortunately, most are scams. To separate the best and worst weight loss pills, we used the following ranking factors:

Science-Backed Ingredients

Dozens of clinical trials back some ingredients. Others are hokey herbal extracts backed by zero scientific evidence. Caffeine, amino acids, fiber, and other natural ingredients are among the best weight loss ingredients available today.

Strong Dosages

Some weight loss supplements contain the right ingredients at the wrong dosages. A supplement might contain 20 good ingredients, but all doses are too small to do anything.

Honest Advertised Weight Loss Effects

If a supplement claims to help you lose 10lbs in a week, it’s probably a scam. We preferred weight loss supplements with honest advertised weight loss effects.

Doctor Formulated or Recommended

A marketing team makes some weight loss pills, while a medical advisory board of doctors, nutritionists, and certified weight-loss specialists make others. Which weight loss pill would you preferably take?

Ease of Use

Some weight loss pills are large. Others have an unpleasant aftertaste. Some require you to take eight capsules per day. Others are easy to use and hassle-free. We considered ease of use when ranking the best weight loss pills of 2022.

Price and Overall Value

Most weight loss pills cost $20 to $100 for a one-month supply. Some people are willing to spend hundreds of dollars per month on a weight loss pill, while others only want to spend $10 to $20. We weren’t biased against specific price ranges. However, we preferred weight loss supplements with good overall value at any price. You should get premium ingredients if you’re paying for a premium supplement. If you’re paying for a budget supplement, you shouldn’t have to compromise on quality.

Clinical Trials and Scientific Evidence

Some of the best weight loss pills are backed by scientific evidence and clinical trials. Most manufacturers do not invest in tests because of the high cost. If a supplement has actual scientific results, it shows it’s one of the best available today.

Money-back Guarantee

If you buy a weight loss pill and don’t lose weight, you should obtain a refund. Virtually all popular weight loss supplements have a 60-day money-back guarantee. If you’re unhappy with the results or did not lose a significant amount of weight, you should be able to request a refund.

After considering all of these factors, we ranked above the best weight loss pills of 2022.

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When, while the lovely valley teems with vapour around me, and the meridian sun strikes the upper surface of the impenetrable foliage of my trees, and but a few stray gleams steal into the inner sanctuary, I throw myself down among the tall grass by the trickling stream; and, as I lie close to the earth, a thousand unknown plants are noticed by me: when I hear the buzz of the little world among the stalks, and grow familiar with the countless indescribable forms of the insects and flies, then I feel the presence of the Almighty, who formed us in his own image, and the breath of that universal love which bears and sustains us, as it floats around us in an eternity of bliss; and then, my friend, when darkness overspreads my eyes, and heaven and earth seem to dwell in my soul and absorb its power, like the form of a beloved mistress, then I often think with longing, Oh, would I could describe these conceptions, could impress upon paper all that is living so full and warm within me, that it might be the mirror of my soul, as my soul is the mirror of the infinite God!

O my friend — but it is too much for my strength — I sink under the weight of the splendour of these visions! A wonderful serenity has taken possession of my entire soul, like these sweet mornings of spring which I enjoy with my whole heart. I am alone, and feel the charm of existence in this spot, which was created for the bliss of souls like mine.

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When, while the lovely valley teems with vapour around me, and the meridian sun strikes the upper surface of the impenetrable foliage of my trees, and but a few stray gleams steal into the inner sanctuary, I throw myself down among the tall grass by the trickling stream; and, as I lie close to the earth, a thousand unknown plants are noticed by me: when I hear the buzz of the little world among the stalks, and grow familiar with the countless indescribable forms of the insects and flies, then I feel the presence of the Almighty, who formed us in his own image, and the breath of that universal love which bears and sustains us, as it floats around us in an eternity of bliss; and then, my friend, when darkness overspreads my eyes, and heaven and earth seem to dwell in my soul and absorb its power, like the form of a beloved mistress, then I often think with longing, Oh, would I could describe these conceptions, could impress upon paper all that is living so full and warm within me.

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O my friend — but it is too much for my strength — I sink under the weight of the splendour of these visions! A wonderful serenity has taken possession of my entire soul, like these sweet mornings of spring which I enjoy with my whole heart. I am alone, and feel the charm of existence in this spot, which was created for the bliss of souls like mine.

I am so happy, my dear friend, so absorbed in the exquisite sense of mere tranquil existence, that I neglect my talents. I should be incapable of drawing a single stroke at the present moment; and yet I feel that I never was a greater artist than now.

When, while the lovely valley teems with vapour around me, and the meridian sun strikes the upper surface of the impenetrable foliage of my trees, and but a few stray gleams steal into the inner sanctuary, I throw myself down among the tall grass by the trickling stream; and, as I lie close to the earth, a thousand unknown plants are noticed by me: when I hear the buzz of the little world among the stalks, and grow familiar with the countless indescribable forms of the insects and flies, then I feel the presence of the Almighty, who formed us in his own image, and the breath of that universal love which bears and sustains us, as it floats around us in an eternity of bliss; and then, my friend, when darkness overspreads my eyes, and heaven and earth seem to dwell in my soul and absorb its power, like the form of a beloved mistress, then I often think with longing, Oh, would I could describe these conceptions, could impress upon paper all that is living so full and warm within me.